COMPLETE ANDROGEN BLOCKADE SAFELY ALLOWS FOR DELAY OF CYTOTOXIC CHEMOTHERAPY IN CASTRATION REFRACTORY PROSTATE CANCER

Complete androgen blockade safely allows for delay of cytotoxic chemotherapy in castration refractory prostate cancer

PURPOSE: Complete androgen blockade (CAB) does not prolong overall survival (OS) in patients with castration refractory prostate cancer (CRPC).Although there is variable clinical benefit with second-line hormone manipulation, we do not know which patients might benefit the most.OBJECTIVES: To identify clinical predictors of benefit of complete andr

read more


Epitope-Tagged Autotransporters as Single-Cell Reporters for Gene Expression by a Salmonella Typhimurium wbaP Mutant.

Phenotypic diversity is an important trait of bacterial populations and can enhance fitness of the existing genotype in a given environment.To characterize different subpopulations, several studies have analyzed differential gene expression using fluorescent reporters.These studies visualized either single or multiple genes within single cells usin

read more


Injection Of air control of propeller performance

With the rise of bubble lubrication technology in transport ships, the interaction between propellers and bubble flow has become increasingly important.On the basis of solving the Reynolds averaged equation and the volume fraction equation, a numerical model of the propeller in a water air mixed fluid was established using the sliding mesh techniqu

read more